Portugal hosts Wales in the League of Nations as the teams meet for the first time since the Euro 2016 semi-finals.
Cristiano Ronaldo scored for Portugal that night en route to a tournament win and the veteran is still going strong at 41.
Wales went unbeaten in the Nations League in 2024-25 and have been promoted as a result.
Portugal is the reigning champion after beating Spain in the last final time.
This is how they line up.
Portugal team news
Cristiano Ronaldo scored 29 goals in 33 appearances under new Portugal manager Jorge Jesus for Al Nassr in the 2025-26 campaign, averaging a goal every 99 minutes.
It starts on the attack when Porto’s goalkeeper, Diogo Costa, gets his head in the goal. Chelsea’s Pedro Neto starts and Manchester United’s talisman Bruno Fernandes.
Portugal XI: Diogo Costa, Nuno Mendes, Rúben Dias, Renato Veiga, João Cancelo, Rúben Neves, Pedro Neto, Vitinha, Bruno Fernandes, João Félix, Cristiano Ronaldo
Wales team news
Goalkeeper Karl Darlow, defenders Joe Rodon and Dylan Lawlor, midfielder Rubin Colwill and forwards Nathan Broadhead, Harry Wilson and Isaak Davies are all injured for Wales.
Danny Ward starts in goal while Ben Davies takes the armband.
Midfielder Jordan James, loaned to Wolves by Rennes, returns to the side.
Wales XI: Danny Ward, Jay Dasilva, Ben Davies, Ben Cabango, Neco Williams, Ethan Ampadu, Josh Sheehan, Jordan James, David Brooks, Brennan Johnson, Lewis Koumas
Where to watch Portugal-Wales: TV channel, live streaming online
Kick-off on Thursday is 19:45 BST (14:45 ET / 11:45 PT). In the UK, live television coverage is on BBC One Wales, BBC Two and S4C.
Streaming on a wide range of devices is available through the BBC iPlayer app and BBC Sport website as well as S4C Online.
For worldwide streaming details, visit International broadcasters of the UEFA Nations League.