Maryland vs. Purdue Prediction, Odds, Picks For College Football Week 10

The Purdue Boilermakers open against the Maryland Terrapins on Saturday in Week 10 college football game on the Big Ten Network.

Let’s take a look at the odds Maryland vs. Purdue at DraftKings Sportsbook as of Nov. 7.

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Money line

• Maryland: +185
• Purdue: -225

SPREAD

• Maryland +5.5: -110
• Purdue -5.5: -110

Over/Under

• Above 56.5: -115
• Under 56.5: -105

From FOX Sports Research:

• Purdue’s Ryan Browne is the third leading passer in the Big Ten with 1,964 yards.
• Maryland has lost six straight games, allowing 39.8 points per game during that span.
• This is just the fifth meeting between Purdue and Maryland.

How to watch Maryland vs. Purdue

• Date: Saturday, November 7, 2026
• Time: 12:30 pm ET
• TV: BTN
• Transmission: Watch 3 days for free on FOX One, FOXSports.comThe FOX Sports app
• Location: Rose-Ade Stadium, West Lafayette, IN