A matchup between the two reigning national champions headlines a busy Week 7 college football slate.
It’s the match we’ve all been waiting for. No. 4 Ohio State faces No. 5 Indiana in a rematch of last year’s Big Ten championship game. Can Jeremiah Smith and the Buckeyes get revenge, or will they? defending national champion Hoosiers give another statement?
SEC also brings us some ranked matches. 6 Alabama could bounce back in Knoxville against No. 14 Tennessee behind her heartbreaking loss to Georgia no. 1 last week? And can Austin Simmons keep Missouri’s No. 13 with a win over his former team, No. 9 Ole Miss?
At night, in the Big 12, No. 18 Oklahoma State will look to continue its rapid rebuild against No. 20 Houston. Meanwhile, No. 2 Notre Dame gets its first big test of the season in a hostile environment in Provo, Utah, against No. 8 BYU. Can the Cougars shock the college football world and continue their undefeated season, or will the Irish extend their nation-leading streak of 16 consecutive double-digit wins?
And out west, UCLA returns home after its biggest win in a decade to host the 4-1 Wisconsin Badgers. With Nico Iamaleava out for the season, can the Bruins keep their momentum behind their backup quarterback?
Here are our experts’ picks for the biggest games of the Week 7 college football season.
2026 Week 7 College Football Experts Picks
College football Saturday in Week 7 features six straight games, headlined by the 2025 Big Ten championship game between No. 4 Ohio State and No. 5 Indiana (noon ET on FOX).